Altered expression of Aquaporin-2 in one-kidney, one-clip hypertension
نویسندگان
چکیده
منابع مشابه
Altered renal expression of aquaporin-2 water channels in rats with experimental two-kidney, one clip hypertension.
The present study was aimed at examining the regulation of aquaporin (AQP)-2 water channels in the kidney in two-kidney, one clip (2K1C) hypertension. Rats were made 2K1C hypertensive for 6 weeks, and their expression of AQP2 channel proteins was determined in the clipped and contralateral kidneys. To examine the upstream affecting AQP2 channels, adenylyl cyclase activity was also determined. A...
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متن کاملAntihypertensive effects of some new nitroxyalkyl 1,4-dihydropyridine derivatives in rat model of two-kidney, one-clip hypertension
Dihydropyridine calcium channel blockers consist one of the widely-used groups of drugs for the management of hypertension. In this study, antihypertensive effects of 5 newly synthesized derivatives of DHP was examined the in rat model of two-kidney, one-clip renal hypertension. The results showed that those compounds containing two nitroxy groups had less decreasing effect on MAP (Men Arterial...
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ژورنال
عنوان ژورنال: Life Sciences
سال: 2018
ISSN: 0024-3205
DOI: 10.1016/j.lfs.2018.07.020